Winning Pick for Lions vs Colts: Breakdown of NFL Game Lines

The Detroit Lions, led by their explosive offense, head to Indianapolis in Week 12 to take on the Colts, and NFL game lines show that Detroit is favored to continue their dominance in the NFC North.

Betting 2024 NFL Week 12 Pick for the Lions vs Colts
NFL Week 12 Fever: Don’t Miss Out on the Betting Action

2024 NFL Season | 104th season of National League in the United States
Week 12: Thursday, November 21st – Monday, November 25th, 2024

Betting 2024 Detroit Lions at Indianapolis Colts | Week 12 Games

The Detroit Lions head to Indianapolis for a Week 12 matchup against the Colts.

Detroit has been dominant this season, sitting at 9-1 and leading the NFC North.

The Lions aim to continue their strong play and solidify their position as one of the league’s top teams.

Indianapolis enters the game at 5-6, still in the mix in the AFC South.

The Colts are looking to build momentum after a narrow win against the Jets last week.

Playing at home, they’ll try to slow down a high-powered Detroit offense that has been unstoppable lately.

Betting on the Betting Odds

Detroit enters the game as a 7.5-point favorite, highlighting their dominance this season.

The Lions’ moneyline is set at -330, while the Colts are +255 underdogs.

The total for the game is 50 points, reflecting the expectation of a high-scoring contest.

Betting trends favor Detroit, which has an 8-2 record against the spread this NFL season.

Meanwhile, Indianapolis has covered in eight of their 11 games but faces a tough challenge against one of the league’s most complete teams.

Betting on the Detroit Lions

The Lions come into this game on an eight-game winning streak, the longest in franchise history since 1934.

Detroit’s offense leads the league, scoring 33.6 points per game.

Jared Goff has been at the center of this success, rebounding from a rough outing two weeks ago with 412 passing yards and four touchdowns last week. (Check out more Quarterback Matchups for NFL Week 12.)

Amon-Ra St. Brown has been a consistent target for Goff, catching touchdowns in eight straight games.

The running game, led by David Montgomery and Jahmyr Gibbs, has also been productive, combining for nearly 1,400 rushing yards and 18 touchdowns this season.

Gibbs is averaging 6.0 yards per carry, providing an explosive element to Detroit’s offense.

Detroit’s defense has held strong despite losing linebacker Alex Anzalone to injury.

The secondary has been effective at limiting big plays, forcing opponents to earn every yard.

However, the absence of Anzalone could make stopping the Colts’ rushing attack more difficult.

Betting on the Indianapolis Colts

The Colts snapped a three-game losing streak with a 28-27 win over the Jets last week.

Quarterback Anthony Richardson returned to the lineup and accounted for three touchdowns, including the game-winning score in the final minute.

Richardson avoided interceptions but struggled with ball security, fumbling twice.

Indianapolis’ offense has relied on Jonathan Taylor to establish the run.

Taylor has been solid but will need a big performance against Detroit’s defense.

Receiver Michael Pittman remains a top target, contributing consistent production even while dealing with minor injuries.

Defensively, the Colts face a major challenge in stopping Detroit’s high-scoring offense.

DeForest Buckner and Grover Stewart anchor the defensive line, but the secondary must improve to contain Goff and his receivers.

Linebackers Zaire Franklin and E.J. Speed will play key roles in slowing down Detroit’s rushing attack.

Detroit Lions vs. Indianapolis Colts Pick & Prediction

This game looks favorable for the Lions, who have been firing on all cylinders.

Their offense has been difficult to stop, and Goff’s ability to spread the ball around should put pressure on the Colts’ defense.

If Detroit’s defense can contain Richardson and limit big plays, they are well-positioned for another win.

Indianapolis will likely put up a fight, but the Lions’ balance on both sides of the ball gives them the advantage.

Expect Detroit to cover the spread and continue their impressive season.

Prediction: Lions 34, Colts 21

Look for more top NFL Rivalries in NFL: Will They Play this Season

Lions vs. Colts Betting Pick

The Colts and Lions always play competitive games, and Sunday’s matchup should be no different.

Indianapolis has home-field advantage and is looking to build momentum, but Detroit’s balanced team and strong coaching give them a shot at an upset.

Enjoy the game and good luck with your betting.

NFL ATS Pick: Detroit -7.5
NFL Total Pick: Over 50

Bet the NFL Week 12 Games | NFL Live Betting MyBookie Betting Lines for the Tournament

^ Top

Lions vs Colts Trends and Insights

Jahmyr Gibbs has hit the Rushing Yards Over in 13 of his last 19 games
Jared Goff has hit the Passing Yards Over in 13 of his last 19 games
Joe Flacco has hit the TD Passes Over in 8 of his last 10 games
Kylen Granson has hit the Receptions Under in his last 7 games at home
Lions have hit the 3Q Game Total Over in 16 of their last 19 games
The Detroit Lions have covered the 1H Spread in 16 of their last 21 games
Colts have covered the Spread in 13 of their last 21 games
Colts have hit the 3Q Moneyline in 6 of their last 9 games at home
Lions are 9-1 when betting on the Moneyline
Lions are 5-4 when betting the Over
Colts are 5-6 when betting on the Moneyline
Colts are 5-6 when betting the Over

Colts vs. Lions Series History

Last meeting:
Lions 21, Colts 41: November 1st, 2020: Week 8 – Ford Field, Detroit, MI

Head-to-head (includes postseason games):
Indianapolis Colts lead series 22-20-2

DETROIT LIONS INJURY UPDATE

Sam LaPorta, Brodric Martin, Iffy Melifonwu, and Emmanuel Moseley are all OUT on Sunday vs. the Jaguars #OnePride pic.twitter.com/OfsXXC7z0E
— Crunch Time Sports (@officialctpod) November 15, 2024

^ Top

Test Your NFL Week 12 Picks with Your MyBookie Account

Stay ahead of the action by checking the NFL betting line Las Vegas for the latest odds and expert picks.

Learn More on NFL Betting
How does it Work?

How to Bet Colts vs Lions Game? Let’s Find Out

Betting on the Colts vs. Lions game is easy!

To place a bet on this exciting NFL Week 12 matchup, you’ll need to sign up with an online sportsbook that offers NFL betting.

Here’s how to get started:

Create an account:
Sign up for a new account by providing your personal information and verifying your identity.
Deposit funds:
Fund your account using your preferred payment method, such as credit card, debit card, or e-wallet.
Find the Colts vs. Lions game:
Navigate to the NFL section of the sportsbook and locate the matchup between the two teams.
Place your bet:
Choose your preferred bet type (e.g., moneyline, point spread, over/under, player props, futures) and wager the desired amount.

For more information on NFL odds, lines, and betting tips, check out our NFL News section.

Once you have an account, you can explore a variety of betting options for this game, including:

Moneyline:
Bet on either the Colts or the Lions to win the game outright.
Point Spread:
Bet on whether the Colts will cover the point spread against the Lions.
Over/Under:
Bet on the total number of points scored in the game.
Player Props:
Bet on individual player performances, such as passing yards, rushing yards, or touchdowns for players like Jonathan Taylor or Amon-Ra St. Brown.
First Score:
Bet on which team will score the first points of the game.
Halftime/Full-Time:
Bet on the outcome of both halves of the game.